The study titled "Pyridoxine and Magnesium Administration–Induced Hyperactivity in Two Children With Autism Spectrum Disorder" from Clinical Therapeutics reports on two cases of children with ASD who exhibited hyperactivity after being administered pyridoxine-Mg. It suggests a possible association between the supplement and hyperactivity. This finding is particularly relevant in light of Brain Brix's formula, which includes both vitamin B6 and magnesium. The study underscores the importance of careful monitoring of supplements, especially in children with neurodevelopmental disorders.

To read the full study for more detailed insights, you can access it here.